1

Stress-Induced Epinephrine Enhances Lactate Dehydrogenase A and Promotes Breast Cancer Stem-Like Cells

Journal of Clinical Investigation，129(3): 1030-1046

Bai Cui#, Yuanyuan Luo#, Pengfei Tian#, Fei Peng#, Jinxin Lu#, Yongliang Yang#, Qitong Su, Bing Liu, Jiachuan Yu, Xi Luo,Liu Yin, Wei Cheng, Fan An, Bin He, Dapeng Liang, Sijin Wu, Peng Chu, Luyao Song, Xinyu Liu, Huandong Luo, Jie Xu, Yujia Pan, Yang Wang, Dangsheng Li, Peng Huang, Qingkai Yang, Lingqiang Zhang, Binhua P. Zhou, Suling Liu, Guowang Xu, Eric W.-F. Lam, Keith W. Kelley, Quentin Liu*

Quentin Liu

2

Multidimensional Liquid Chromatography-Mass Spectrometry for Metabolomics and Lipidomics

Trac-Trends in Analytical Chemistry，120: 115302.1-14

Wangjie Lv #, Xianzhe Shi #, Shuangyuan Wang, Guowang Xu *

Guowang Xu

3

New Advances in Analytical Methods for Mass Spectrometry-Based Large-Scale Metabolomics Study

Trac-Trends in Analytical Chemistry，121: 115665.1-11

Xinyu Liu, Linan Zhou, Xianzhe Shi, Guowang Xu

Guowang Xu

4

ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCb3 Catalysis: Targeting It Eradicates Leukemia Stem Cells

Cell Reports，26: 2166-2177

Wenbin Zhong,Mengyang Xu,Chanjuan Li,Biying Zhu,Xiuye Cao,Dan Li,Huanzhao Chen,Chunxiu Hu,Rong Li,Chengwei Luo,Guoping Pan,Wenqiang Zhang,Chaofeng Lai,Tong Wang,Xin Du,Hong Chen,Guowang Xu,Vesa M. Olkkonen,Daoguang Yan*

Daoguang Yan

5

Metabolomics Profiling of Metformin-Mediated Metabolic Reprogramming Bypassing AMPKα

Metabolism-Clinical and Experimental，91: 18-29

Min Yan, Huan Qi, Tian Xia, Xinjie Zhao,Wen Wang, ZhichaoWang, Chang Lu, Zhen Ning,Huan Chen, Tongming Li, Dinesh Singh Tekcham, Xiumei Liu, Jing Liu , Di Chen, Xiaolong Liu,Guowang Xu *, Hai-long Piao*

Guowang Xu , Hai-long Piao

6

Characteristics of bile acids metabolism profile in the second and third trimesters of normal pregnancy

Metabolism-Clinical and Experimental，95: 77-83

Bo Zhu#, Peiyuan Yin#, Zhixin Ma, Yu Ma, Hong Zhang, Hongwei Kong, Yuning Zhu*

Yuning Zhu

7

Removal of False Positive Features to Generate Authentic Peak Table for High-resolution Mass Spectrometry-based Metabolomics Study

Analytica Chimica Acta，1067: 79-87

Ran Ju, Xinyu Liu, Fujian Zheng, Xinjie Zhao, Xin Lu, Zhongda Zeng*, Xiaohui Lin*, Guowang Xu*

Zhongda Zeng, Xiaohui Lin, Guowang Xu

8

Comprehensive Profiling by Non-targeted Stable Isotope Tracing Capillary Electrophoresis-Mass Spectrometry: A New Tool Complementing Metabolomic Analyses of Polar Metabolites

Chemistry-A European Journal，25: 5427-5432

Jun Zeng#, Zhichao Wang#, Xin Huang, Sabine S. Eckstein, Xiaohui Lin, Hailong Piao, Cora Weigert, Peiyuan Yin, Rainer Lehmann*, Guowang Xu*

Rainer Lehmann, Guowang Xu

9

A Comprehensive Strategy for Studying Protein-Metabolite Interactions by Metabolomics and Native Mass Spectrometry

Talanta，194: 63-72

Qian Qin, Bohong Wang, Jiayue Wang, Mengmeng Chang, Tian Xia, Xianzhe Shi, Guowang Xu

Chunxia Zhao, Xiaohui Lin, Guowang Xu

10

Linking Bioenergetic Function of Mitochondria to Tissue-Specific Molecular

Fingerprints

American Journal of Physiology Endocrinology and Metabolism，317: E374–E387

Lisa Kappler, Miriam Hoene, Chunxiu Hu, Christine von Törne, Jia Li, Daniel Bleher, Christoph Hoffmann, Anja Böhm, Laxmikanth Kollipara, Hans Zischka, Alfred Königsrainer, Hans-Ulrich Häring, Andreas Peter, Guowang Xu, Albert Sickmann, Stefanie Hauck, Cora Weigert, Rainer Lehmann

Rainer Lehmann

11

Metabolic Profiling Reveals Distinct Metabolic Alterations in Different Subtypes of Pituitary Adenomas and Confers Therapeutic Targets

Journal of Translational Medicine，17: 291.1-291.13

Jie Feng, Hua Gao, Qi Zhang, Yang Zhou, Chuzhong Li, Sida Zhao, Lichuan Hong, Jinjin Yang, Shuyu Hao, Wan Hong, Zhengping Zhuang, Guowang Xu, Yazhuo Zhang

Guowang Xu, Yazhuo Zhang

12

Metabolic Phenotypes and The Gut Microbiota in Response to Dietary Resistant Starch Type 2 in Normal-Weight Subjects: A Randomized Crossover Trial

Scientific Reports，9: 4736.1-4736.11

Lei Zhang, Yang Ouyang, Huating Li, Li Shen, Yueqiong Ni, Qichen Fang, Guangyu Wu, Lingling Qian, Yunfeng Xiao, Jing Zhang, Peiyuan Yin, Gianni Panagiotou, Guowang Xu, Jianping Ye , Weiping Jia

Huating Li, Guowang Xu, Weiping Jia

13

Modified Metabolites Mapping by Liquid Chromatography-High Resolution Mass Spectrometry Using Full Scan/All Ion Cheek for Fragmentation/Neutral Loss Acquisition

Journal of Chromatography A，1583: 80-87

Hua Li, Qian Qin, Xianzhe Shi, Jun He, Guowang Xu

Xianzhe Shi

14

Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation

Journal of Proteome Research，18: 960-969

Lina Zhou, Zhichao Wang, Chunxiu Hu, Chaoqi Zhang, Petia Kovatcheva-Datchary, Shasha Liu, Feifei Ren, Di Yu, Peiyuan Yin, Xiaolin Wang,Yanli Li, Xiaoli Hou, Hailong Piao, Xin Lu, Yi Zhang, Guowang Xu

Yi Zhang, Guowang Xu

15

Serum Metabolomics Study of Nonsmoking Female Patients with Non-Small Cell Lung Cancer Using Gas Chromatography–Mass Spectrometry

Journal of Proteome Research，18: 2175-2184

Ying Mu, Yang Zhou, Yanfeng Wang, Wei Li, Lina Zhou, Xin Lu, Peng Gao, Mingyang Gao, Yanhui Zhao, Qi Wang, Yanfu Wang, Guowang Xu

Yanfu Wang, Guowang Xu

16

Metabolic Profiling Reveals Biochemical Pathways and Potential Biomarkers of Spinocerebellar Ataxia 3

Frontiers in Molecular Neuroscience，12: 159.1-159.10

Zhihua Yang, Changhe Shi, Lina Zhou, Yusheng Li, Jing Yang, Yutao Liu, Chengyuan Mao, Haiyang Luo, Guowang Xu, Yuming Xu

Guowang Xu, Yuming Xu

17

Sex-Specific Plasma Metabolome Signatures in Major Depressive Disorder

Psychiatry and Clinical Neurosciences，73: 713-720

Juncai Pu, Xinyu Liu, Yiyun Liu, Siwen Gui, Xiaogang Zhong, Lu Tian, Lining Yang, Shaohua Xu, Xuemian Song, Xiang Chen, Yue Chen, Haiyang Wang, Guowang Xu, Peng Xie

Guowang Xu, Peng Xie

18

A Novel Analysis Method for Biomarker Identification Based on Horizontal Relationship: Identifying Potential Biomarkers From Large-Scale Hepatocellular Carcinoma Metabolomics Data

Analytical and Bioanalytical Chemistry，411: 6377-6386

Benzhe Su, Ping Luo, Zhao Yang, Pei Yu, Zaifang Li, Peiyuan Yin, Lina Zhou, Jinhu Fan, Xing Huang, Xiaohui Lin, Youlin Qiao, Guowang Xu

Peiyuan Yin, Jinhu Fan, Xiaohui Lin

19

Carboxymethylated Polyethylenimine Modified Magnetic Nanoparticles Specifically for Purification of His-Tagged Protein

Journal of Separation Science，42: 744-753

Mengmeng Chang, Qian Qin, Bohong Wang, Tian Xia, Wangjie lv, Xiaoshan Sun, Xianzhe Shi, Guowang Xu

Xianzhe Shi

20

Metabolomics of Lung Cancer: Analytical Platforms and Their Applications

Journal of Separation Science，1-14

Hamada A. A. Noreldeen, Xinyu Liu, Guowang Xu

Xinyu Liu

21

Serum Metabolome and Targeted Bile Acid Profiling Reveals Potential Novel Biomarkers for Drug-Induced Liver Injury

Medicine，98:

e16717.1-e16717.11

Zhenhua Ma,Xiaomei Wang, Peiyuan Yin, Ruihong Wu, Lina Zhou, Guowang Xu, Junqi Niu

Guowang Xu, Junqi Niu

22

细胞蛋白质组学和代谢组学整合策略表征散斑型BTB/POZ蛋白质突变调控的关键代谢通路

色谱，37: 887-896

颜敏,刘静,夏天,许国旺,朴海龙

朴海龙

23

基于质谱技术对垂体嗜酸性细胞瘤异常代谢通路的研究

中华神经外科杂志，35: 395-399

杨晶晶，冯洁，周洋，洪礼传，于升远，徐宁，许国旺，张亚卓

张亚卓